DMT (N, N-dimethyltryptamine) is a psychedelic drug with short-lived hallucinogenic effects. It is commonly used in traditional ceremonies, particularly those using ayahuasca, a plant that contains DMT and is drunk as a tea. Taking large doses of DMT can result in intense or unpleasant effects, though these typically don’t lead to overdose or death. However, combining DMT with certain substances may increase the risk of adverse physical and/or psychological effects.